The mass media are considered to be one of the most important agenda setters in this society. They steer the attention of the public toward certain political issues using repetition, emphasis, and ordering of the articles. How much of the article selections of the news consumers is driven by pure “salience,” and how much is via more conscious process such as issue delegation (media guide the news consumers)? How much of the selection is driven by the subjective issue importance of the news consumers prior to seeing the media emphasis of the issues? Do media's issue “salience” and “guidance” affect the subjective importance of the issues, opinions on policy issues, and eventually the support for the political parties? Through an Amazon Mechanical Turk (MTurk) experiment in the US, this paper aims to answer these questions in a systematic and coherent way.