Cognitive Crescendo: Unravelling the Effect of Music Induction on Dementia and Depression-Associated Cognitive and Psychological Problems: An Experimental Study

Last registered on January 02, 2024
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Pre-Trial

Trial Information

General Information

Title
Cognitive Crescendo: Unravelling the Effect of Music Induction on Dementia and Depression-Associated Cognitive and Psychological Problems: An Experimental Study
RCT ID
AEARCTR-0012759
Initial registration date
December 28, 2023

Initial registration date is when the trial was registered.

It corresponds to when the registration was submitted to the Registry to be reviewed for publication.

First published
January 02, 2024, 11:00 AM EST

First published corresponds to when the trial was first made public on the Registry after being reviewed.

Locations

Country
Pakistan
Region
Punjab

Primary Investigator

Name
Hira Afaq
Affiliation
Contact Primary Investigator

Other Primary Investigator(s)

PI Name
Muhammad Aqeel
PI Affiliation
Supervisor
Contact Investigator

Additional Trial Information

Status
On going
Start date
2023-11-29
End date
2024-01-03
Keywords
Behavior
Additional Keywords
cognitive problem, psychological problem, dementia, depression, music, positive emotion, negative emotion, cognitive processes
JEL code(s)
Secondary IDs
Prior work
This trial does not extend or rely on any prior RCTs.
Abstract
Background:
Dementia and depression are highly prevalent and interconnected conditions among adults and are associated with individuals’ distress and rising mental health conditions in Pakistan. Effective, saleable and feasible interventions are needed. Music based interventions have shown promising effects, but the current evidence base is inconclusive. The present study aimed to determine the effectiveness of different music interventions on the depressive symptoms of people with dementia and depression.
Method:
This study used a simple random sampling technique, randomized controlled trial. Thirty participants will be recruited from psychiatric departments in Rawalpindi. They will be equally divided into two groups: control group and experimental group. In controlled group (15 participants) the data will be collected from normal population and in experimental group (15 participants) the data will be collected from dementia patients having comorbid symptoms of depression. To assess the intervention four block designed will be created in which participants will experience positive and negative music-visual induction on Psychopy. The study employed a two-way factorial analysis of variance (ANOVA) to evaluate the effectiveness of music intervention in reducing symptoms, improving cognitive insight and enhancing quality of life.
External Link(s)

Registration Citation

Citation
Afaq, Hira and Muhammad Aqeel. 2024. "Cognitive Crescendo: Unravelling the Effect of Music Induction on Dementia and Depression-Associated Cognitive and Psychological Problems: An Experimental Study." AEA RCT Registry. January 02. https://doi.org/10.1257/rct.12759-1.0
Sponsors & Partners
Experimental Details

Interventions

Intervention(s)
Beck Depression inventory
Dementia severity rating scale
PANAS
Positive and Negative visual and auditory intervention
Intervention Start Date
2023-11-29
Intervention End Date
2023-12-31

Primary Outcomes

Primary Outcomes (end points)
severity reduction of dementia and depression levels
Primary Outcomes (explanation)
severity reduction of dementia and depression levels through musical and visual interventions

Secondary Outcomes

Secondary Outcomes (end points)
Secondary Outcomes (explanation)

Experimental Design

Experimental Design
Beck depression inventory
Dementia Severity Rating Scale
PANAS
Positive and Negative Auditory and Visual intervention
Experimental Design Details
Block 1 = Positive Music Induction
Intervention: Participants will be exposed to positively valence music (cheerful tunes).
Duration: The intervention will last for a predetermined period (20 seconds) while participants engage with the music.
Block 2 = Positive Visual Induction
Intervention: Participants will be exposed to positive image.
Duration: The intervention will last for a predetermined period (20 seconds) while participants focus on positive image.
Block 3: Negative Music Induction
Intervention: Participants will be exposed to negatively valence music (dissonant tones).
Duration: The intervention will last for a predetermined period (20 seconds) while participants engage with the music.
Block 4 = Negative Visual Induction
Intervention: Participants will be exposed to negative image.
Duration: The intervention will last for a predetermined period (20 seconds) while participants focus on negative image.
T2 = Dementia Severity Rating Scale (DSRS)
Assessment: After the intervention, participants will complete the Dementia Severity Rating Scale to assess their dementia severity symptoms.
Block 5: Negative Music Induction + Positive Visual Induction
Intervention: Participants will experience the negative music (30 seconds) as in Block 3 but paired with positive visual stimuli (joyful scenes).
Duration: The duration of the intervention will remain constant to isolate the impact of the stimuli combination.
T3 = Positive and Negative Affect Schedule (PANAS)
Assessment: The effect of positive and negative visual-auditory induction is measured by positive and negative affect schedule (PANAS).
Block 4: Positive Music Induction + Negative Visual Induction
Intervention: Participants will listen to positively valence music (30 seconds) similar to Block 1 but paired with negative visual stimuli (distressing images).
Duration: Consistent timing will be applied to this intervention block for accurate comparison with the other blocks.
T4 = Positive and Negative Affect Schedule (PANAS)
Assessment: The effect of positive and negative visual-auditory induction is measured by positive and negative affect schedule (PANAS).
Randomization Method
simple random sampling technique
Randomization Unit
different hospitals and psychological clinics from Rawalpindi and Islamabad, Pakistan
Was the treatment clustered?
Yes

Experiment Characteristics

Sample size: planned number of clusters
4 hospitals 2 clinics
Sample size: planned number of observations
15 normal and 15 dementia and depression patients
Sample size (or number of clusters) by treatment arms
15 controlled normal people from different hospitals and 15 experimental dementia and depression patients
Minimum detectable effect size for main outcomes (accounting for sample design and clustering)
Supporting Documents and Materials

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IRB

Institutional Review Boards (IRBs)

IRB Name
IRB Approval Date
IRB Approval Number
Analysis Plan

Post-Trial

Post Trial Information

Study Withdrawal

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Intervention

Is the intervention completed?
No
Data Collection Complete
Data Publication

Data Publication

Is public data available?
No

Program Files

Program Files
Reports, Papers & Other Materials

Relevant Paper(s)

Reports & Other Materials