Ghana Tuberculosis Screening Trail Follow-up

Last registered on October 18, 2024

Pre-Trial

Trial Information

General Information

Title
Ghana Tuberculosis Screening Trail Follow-up
RCT ID
AEARCTR-0014570
Initial registration date
October 14, 2024

Initial registration date is when the trial was registered.

It corresponds to when the registration was submitted to the Registry to be reviewed for publication.

First published
October 18, 2024, 5:04 PM EDT

First published corresponds to when the trial was first made public on the Registry after being reviewed.

Locations

Region

Primary Investigator

Affiliation
University of Oxford

Other Primary Investigator(s)

PI Affiliation
LSE

Additional Trial Information

Status
In development
Start date
2024-10-23
End date
2024-11-15
Secondary IDs
Prior work
This trial does not extend or rely on any prior RCTs.
Abstract

We designed and implemented the Tuberculosis Screening RCT to explore how cost calculations shape the decision to comply with public health measures. The study will be referred to as Wave IIa. This initial trial registration is AEARCTR-0013055 (\url{https://www.socialscienceregistry.org/trials/13055}). A draft of the initial results is available \url{https://raymondduch.com/files/Ghana-Tuberculosis-Screening_Oct-2024.pdf}. In this amended pre-registration we are proposing the implementation of additional data collection that would allow us to test more directly the effect of individualized messaging. This study will be referred to as Wave IIb.

This registration describes the implementation of a follow-up study that would facilitate the estimation of the spillover effect of the enumerator messaging interventions. The additional data collection adds a control arm with no enumerator messaging intervention. We will then implement a version of the original cluster randomized RCT that has only two arms: In the control arm, 30 villages are treated with a two-day pop-up clinic that includes broadcasting announcements of the clinic location and dates (identical to those employed in the original Wave IIa version of the RCT). In the treatment arm, administered to 25 villages, 26 randomly selected individuals in each village receive the identical health messaging plus telephone reminder treatment administered in the original Wave IIa trial.

Registration Citation

Citation
Duch, Raymond and Thomas Robinson. 2024. "Ghana Tuberculosis Screening Trail Follow-up." AEA RCT Registry. October 18. https://doi.org/10.1257/rct.14570-1.0
Experimental Details

Interventions

Intervention(s)
This registration describes the implementation of a follow-up study that would facilitate the estimation of the spillover effect of the enumerator messaging interventions. The additional data collection adds a control arm with no enumerator messaging intervention. We will then implement a version of the original cluster randomized RCT that has only two arms: In the control arm, 30 villages are treated with a two-day pop-up clinic that includes broadcasting announcements of the clinic location and dates (identical to those employed in the original Wave IIa version of the RCT). In the treatment arm, administered to 25 villages, 26 randomly selected individuals in each village receive the identical health messaging plus telephone reminder treatment administered in the original Wave IIa trial.
Intervention (Hidden)
Intervention Start Date
2024-10-31
Intervention End Date
2024-11-08

Primary Outcomes

Primary Outcomes (end points)
getting a tuberculosis screening during the ttwo-data pop-up TB screening clinic in the participant's village
Primary Outcomes (explanation)

Secondary Outcomes

Secondary Outcomes (end points)
Secondary Outcomes (explanation)

Experimental Design

Experimental Design
This registration describes the implementation of a follow-up study that would facilitate the estimation of the spillover effect of the enumerator messaging interventions. The additional data collection adds a control arm with no enumerator messaging intervention. We will then implement a version of the original cluster randomized RCT that has only two arms: In the control arm, 30 villages are treated with a two-day pop-up clinic that includes broadcasting announcements of the clinic location and dates (identical to those employed in the original Wave IIa version of the RCT). In the treatment arm, administered to 25 villages, 26 randomly selected individuals in each village receive the identical health messaging plus telephone reminder treatment administered in the original Wave IIa trial.
Experimental Design Details
Full design is available in the attached pdf document.
Randomization Method
Full description in attached pdf document
Randomization Unit
Village and individual in cluster randomized design. Full description in attached pdf document.
Was the treatment clustered?
Yes

Experiment Characteristics

Sample size: planned number of clusters
55
Sample size: planned number of observations
650
Sample size (or number of clusters) by treatment arms
25 in treatment
30 in control
full description in attached pdf document
Minimum detectable effect size for main outcomes (accounting for sample design and clustering)
0.015
Supporting Documents and Materials

Documents

Document Name
Ghana_Tuberculosis_Screening_Wave_IIb
Document Type
proposal
Document Description
The complete pre-registration description is available in this document.
File
Ghana_Tuberculosis_Screening_Wave_IIb

MD5: a83bdf7ed3605936d2cd9fab2fc1f5b5

SHA1: da9a789b17c945298327ceec23378917462812de

Uploaded At: October 14, 2024

IRB

Institutional Review Boards (IRBs)

IRB Name
Oxford CUREC
IRB Approval Date
2023-04-27
IRB Approval Number
R82364/RE002
Analysis Plan

Analysis Plan Documents

Ghana Tuberculosis Screening Wave IIb

MD5: a83bdf7ed3605936d2cd9fab2fc1f5b5

SHA1: da9a789b17c945298327ceec23378917462812de

Uploaded At: October 14, 2024

Post-Trial

Post Trial Information

Study Withdrawal

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Intervention

Is the intervention completed?
No
Data Collection Complete
Data Publication

Data Publication

Is public data available?
No

Program Files

Program Files
Reports, Papers & Other Materials

Relevant Paper(s)

Reports & Other Materials