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Fields Changed

Registration

Field Before After
Trial Start Date October 06, 2025 March 17, 2026
Trial End Date January 12, 2026 June 06, 2026
Last Published April 02, 2026 05:37 PM June 26, 2026 04:38 PM
Study Withdrawn No
Intervention Completion Date June 04, 2026
Data Collection Complete Yes
Final Sample Size: Number of Clusters (Unit of Randomization) no clusters
Was attrition correlated with treatment status? No
Final Sample Size: Total Number of Observations 149 participants analyzed for the primary outcome (84 control, 65 treatment). Up to 183 had an endline ASA24 recall (the outcome); 149 also had a matched baseline HEI.
Final Sample Size (or Number of Clusters) by Treatment Arms Randomized: 967 control / 945 treatment. Analyzed (primary outcome): 84 control / 65 treatment.
Is there a restricted access data set available on request? Yes
Restricted Data Contact [email protected]
Program Files No
Data Collection Completion Date June 06, 2026
Is data available for public use? No
Intervention Start Date October 13, 2025 April 17, 2026
Intervention End Date January 05, 2026 June 04, 2026
Experimental Design (Public) We will recruit 1,400 U.S. adults through the Forthright platform. After an eligibility screener (≥ 18 y, English-speaking, owns a smartphone, no diet restrictions), Forthright’s server-side block randomizer will assign participants 1: 1 to two parallel arms: • Treatment arm – full AI-Nutrition app with real-time, personalized meal suggestions generated by AI and natural-language-processing algorithms. • Control arm – only receives general dietary suggestions (e.g., USDA MyPlate tip sheets). The study design is single blind from the participants’ side. Participants will be blind to allocation; they are told only that they will receive “nutrition guidance”. The control arm is not informed that another group uses an app. Forthright and our technology team will see and handle the randomization and allocations, while the data analysis team will be masked to the arm codes. We will collect dietary intake along with several behavioral questions at the baseline (Week 0, before app access) and the post-intervention point (Week 12). The dietary intake will be collected with the ASA24 24-hour recall, and the behavioral questions will be given to study participants to assess their eating habits. The treatment arm participants will be instructed to use the app at least once per week and indicate whether they followed each personalized recommendation. App analytics (log-ins, screen views, session length) will be logged automatically for subsequent engagement analyses. Data-collection schedule Study week Assessment Mode Approx. time 0 (baseline) ASA24® 24-h recall; demographics; eating-behavior questionnaire Forthright survey link 20 min 1 – 12 App use (Treatment arm) + engagement logging In-app 5 min per use 12 (post) ASA24® 24-h recall; user-experience items Forthright survey link 20 min We will screen approximately 1,900 U.S. adults through the Forthright Access platform. After an eligibility screener (≥ 18 years; basic English; regular smartphone and internet access; generally healthy adults for whom the Dietary Guidelines for Americans are appropriate — excluding those requiring medically supervised or restrictive diets, e.g., diabetes, celiac/gluten sensitivity, CKD requiring dietary restriction, prescribed or highly restrictive diets, or pregnancy), Forthright's server-side block randomizer will assign eligible participants 1:1 to two parallel arms. Accounting for ≈50% eligibility and ≈10% attrition, we anticipate an analytic sample of ≈780 (≈390 per arm). Both arms use the same mobile/web application, which includes a Track Mode for all participants (log meals; view nutrient and diet-quality summaries) and a Personalized Recommendation Mode for the treatment arm only. Treatment arm – the app with Track Mode plus the AI/NLP-driven Personalized Recommendation Mode (OpenAI engine constrained to USDA FPED, the Dietary Guidelines, and AMDR ranges; educational only). Control arm – the same app shell in Track Mode only (tracking + general, non-personalized guidance); no AI-personalized recommendations. Single-blind from the participant's side; participants are told only that they will receive "nutrition guidance"; the control arm is not informed another group receives AI recommendations. Forthright/the technology team handle randomization; the data-analysis team is masked to arm codes. Dietary intake and behavioral questions are collected at baseline (Week 0) and at the post-intervention endline [registered Week 12; implemented after ~7 weeks under the approved modification]. Intake is measured with ASA24; treatment participants are asked to use the app ≥ once/week and to indicate whether they followed each recommendation; app analytics are logged automatically for engagement/uptake analyses.
Randomization Method Forthright algorithm Randomization was performed by the research team, using a computer-generated, stratified randomization procedure implemented in R with a fixed seed for reproducibility. Eligible participants who passed the electronic screener and provided e-consent were stratified by gender, age group (18–34, 35–49, 50+), and household income group (<$35k, $35k–$74k, $75k–$149k, ≥$150k); within each stratum (the cross-classification of gender × age × income), participants were allocated 1:1 to the treatment and control arms by random permutation of balanced assignment labels. Forthright provided panel recruitment and survey administration only; the study team generated and managed the allocation sequence and arm assignments. Participants were blind to allocation (single-blind from the participant side), and the data-analysis team was masked to the arm codes. Original structure (as registered). Each completed survey earned $2.50 plus one loyalty point. Participants who completed both the baseline and endline surveys qualified for an app-engagement reward based on their app activity: the top 1% → $50, those ranked top 1–10% → $5, with ties split equally. Modification at the (early) endline. End-survey incentives were augmented: the first 200 eligible participants who fully completed the end survey by Thursday, June 4, 2026 received $15 each, and all who completed it by that date were entered into a random drawing for one $150 gift card — in addition to the original app-engagement rewards (top 1% → $50; top 10% → $5).
Randomization Unit Two arms are included: (1) Control – intake tracking app and general advice, and (2) Treatment – intake tracking app plus AI-generated dietary advice. Two arms are included: Treatment arm — the app with Track Mode and the AI-driven Personalized Recommendation Mode: real-time personalized meal suggestions from an LLM/NLP engine (OpenAI) constrained to USDA FPED, the Dietary Guidelines, and AMDR ranges (educational only). Control arm — the same app shell in Track Mode only (tracking features + general, non-personalized guidance); no AI-personalized recommendations.
Planned Number of Clusters Primary design is individual-level randomization via Forthright. If operational constraints require batching or geographic assignment that induces clustering, we will amend the registry to specify the cluster unit and count and will use cluster-robust SEs accordingly. Not applicable — individual-level randomization (no clustering). The unit of randomization is the individual participant; participants were stratified by gender × age × income and assigned 1:1 within strata.
Intervention (Hidden) We will recruit 1,400 U.S. adults through the Forthright platform. After an eligibility screener (≥ 18 y, English-speaking, owns a smartphone, no diet restrictions), Forthright’s server-side block randomizer will assign participants 1: 1 to two parallel arms: • Treatment arm – full AI-Nutrition app with real-time, personalized meal suggestions generated by AI and natural-language-processing algorithms. • Control arm – only receives general dietary suggestions (e.g., USDA MyPlate tip sheets). The study design is single blind from the participants’ side. Participants will be blind to allocation; they are told only that they will receive “nutrition guidance”. The control arm is not informed that another group uses an app. Forthright and our technology team will see and handle the randomization and allocations, while the data analysis team will be masked to the arm codes. We will collect dietary intake along with several behavioral questions at the baseline (Week 0, before app access) and the post-intervention point (Week 12). The dietary intake will be collected with the ASA24 24-hour recall, and the behavioral questions will be given to study participants to assess their eating habits. The treatment arm participants will be instructed to use the app at least once per week and indicate whether they followed each personalized recommendation. App analytics (log-ins, screen views, session length) will be logged automatically for subsequent engagement analyses. We will screen approximately 1,900 U.S. adults through the Forthright Access platform. After an eligibility screener (≥ 18 years; basic English; regular access to a smartphone and internet; generally healthy adults for whom the Dietary Guidelines for Americans are appropriate — excluding individuals requiring medically supervised or restrictive diets, e.g., diabetes, celiac disease/gluten sensitivity, chronic kidney disease requiring dietary restriction, prescribed/highly-restrictive diets, or pregnancy), Forthright's server-side block randomizer will assign eligible participants 1:1 to two parallel arms. We anticipate an analytic sample of approximately 780 (~390 per arm). Both arms use the same mobile/web application. It has two components: a Track Mode for all participants (log meals, view nutrient and diet-quality summaries) and a Personalized Recommendation Mode for the treatment arm only. Treatment arm — the app with Track Mode and the AI-driven Personalized Recommendation Mode: real-time personalized meal suggestions from an LLM/NLP engine (OpenAI) constrained to USDA FPED, the Dietary Guidelines, and AMDR ranges (educational only). Control arm — the same app shell in Track Mode only (tracking features + general, non-personalized guidance); no AI-personalized recommendations. Single-blind from the participant's side; the data-analysis team is masked to arm codes. Dietary intake and behavioral items are collected at baseline (Week 0) and at the post-intervention endline [registered Week 12; implemented after ~7 weeks under the approved modification]. Intake is measured with ASA24; treatment participants are asked to use the app ≥ once/week and indicate whether they followed each recommendation; app analytics are logged automatically. Emails are collected only for app registration and reminders.
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