Experimental Design Details
The study is a laboratory experiment designed to evaluate how the medium of communication and the identity of the messenger influence the reception of a public health message about vaccination.
Participants are recruited from the student population of a large university and participate in laboratory sessions conducted at the laboratory of the Athens University of Economics and Business. Each participant completes the study individually at a laboratory workstation. Participants assigned to the virtual reality condition use a head-mounted VR device, while participants assigned to the video condition or the control condition view the content on a standard computer monitor.
The study follows a mixed experimental design combining between-participant and within-participant variation.
The between-participant dimension randomizes the communication medium:
Virtual Reality (VR): participants experience the message in an immersive virtual environment using a VR headset.
Video: participants watch the same message presented as a standard two-dimensional video on a computer screen embedded in the survey interface.
Control: participants watch a neutral video embedded in the survey.
Participants assigned to the information treatment (i.e., those in the Video or VR groups) are randomly assigned to receive the same health message from either:
a medical expert (scientist) – a physician or medical researcher;
a professional social media influencer – a public communicator with a large online following.
The speakers are real individuals and appear as recorded videos of themselves delivering the message. The informational script is identical across speakers and conditions to ensure that message content is constant across treatments, except for participants in the control group who do not receive the health message.
The experimental session consists of three main stages.
Pre-treatment survey
Participants complete a baseline questionnaire collecting demographic information, prior beliefs about vaccines, trust in institutions, social media use, information sources, knowledge of influencers, health-related behaviors, and social network information. The questionnaire includes the following categories of questions:
Administrative and participation information
session number assigned by the laboratory assistants
participant user ID
confirmation of consent and participation
Demographic and family background
year of birth
gender
role at the Athens University of Economics and Business (e.g., undergraduate student, postgraduate student, teaching staff)
department affiliation within the university
postgraduate program of study, where applicable
prefecture of origin in Greece
political ideology
mother's education and father's education
mother's occupation and father's occupation
family income category
The family background variables are collected using categorical response options. Parental occupations are recorded using broad occupational categories, including non-employment.
Baseline beliefs about vaccines
Participants report, on 0–10 scales ("not at all" to "completely"), the extent to which they believe that vaccines are:
effective at preventing pandemics and serious diseases
safe for individual health
important for their own health
important for public health
Trust in health-related institutions and information sources
Participants report their level of trust, on 0–10 scales, in:
conventional medicine and surgery
healthcare professionals
public health authorities
information obtained from social media
Social media use
Participants report their use of social media through several measures:
frequency of use, recorded on a 4-category scale: never; rarely (no more than once a week); often (more than once a week); every day or almost every day
time spent on social media on a typical day, recorded on a 6-category scale: less than 30 minutes; 30–59 minutes; 1–2 hours; 2–3 hours; 3–5 hours; more than 5 hours
main purpose of social media use, including whether it is used mainly for entertainment, information/news, or other purposes
Source of information
Participants are asked where they usually obtain information and news, including whether social media is their main source of information versus other sources. These variables are used to distinguish individuals who primarily rely on social media for information from those who rely more on traditional or other sources. This distinction is also reflected in the heterogeneity analyses described in the presentation materials.
Knowledge and familiarity with influencers
Before treatment, participants are asked about a set of well-known Greek influencers and public figures. For each person, they report:
familiarity, measured on a 4-point scale ranging from "I do not know this person" to "extremely familiar"
overall opinion, measured on a 5-point scale ranging from -2 (very negative) to +2 (very positive)
Health-related behaviors
Participants report:
smoking behavior during the last 30 days
physical exercise during the last 30 days
These variables are collected as ordered categorical measures of recent behavior.
Vaccination-related attitudes and past behavior
Participants answer baseline questions on their vaccination-related attitudes and prior behavior. In the follow-up survey, all participants are asked whether they are more willing to get vaccinated than before and whether they have received any additional vaccines since the main study period.
Social network information
Participants are asked to list up to 10 friends who also attend the Athens University of Economics and Business. For each listed friend, the survey collects:
first name and surname
time spent together in a typical university week outside class, measured on a 7-category scale from 0 hours to more than 20 hours
type of relationship, measured on a 4-category scale: mainly social/personal; mainly academic; both but mostly social; both but mostly academic
closeness to the friend, measured on an ordered response scale
Questions related to the evaluation of the speaker, evaluation of the message, perceived credibility of the messenger, and willingness to discuss the issues raised in the intervention are asked only after the informational exposure and therefore only for participants assigned to the Video or VR treatment groups.
Informational exposure
Participants are exposed to the public health message delivered by the speakers according to their assigned medium condition (VR or Video). Participants in the control group watch a neutral video lasting approximately 1.5 minutes.
Post-treatment survey
Immediately after the informational exposure, participants complete a questionnaire measuring the main outcomes of interest, including trust in vaccines, trust in the healthcare system, willingness to discuss vaccination-related topics with others, evaluation of the message and the speaker, and perceived credibility of the speaker.
For participants in the VR condition, the system also records behavioral engagement measures including eye-tracking and gaze direction. These measures allow the study to examine mechanisms related to attention and engagement during the informational exposure.
Participants receive a fixed participation payment and are entered into a lottery to win several Apple products.
Two months after the laboratory session, participants are contacted to complete a follow-up survey. The follow-up survey collects information on participants' willingness to vaccinate and their self-reported vaccination status, allowing us to examine whether the effects of the informational intervention persist and translate into vaccination intentions and behavior over time.