Distance, price and healthcare use in rural areas

Last registered on December 09, 2025

Pre-Trial

Trial Information

General Information

Title
Distance, price and healthcare use in rural areas
RCT ID
AEARCTR-0017388
Initial registration date
December 03, 2025

Initial registration date is when the trial was registered.

It corresponds to when the registration was submitted to the Registry to be reviewed for publication.

First published
December 09, 2025, 7:33 AM EST

First published corresponds to when the trial was first made public on the Registry after being reviewed.

Locations

Primary Investigator

Affiliation
LSE

Other Primary Investigator(s)

Additional Trial Information

Status
On going
Start date
2025-07-01
End date
2026-09-30
Secondary IDs
Prior work
This trial does not extend or rely on any prior RCTs.
Abstract
Millions of people in rural areas face major barriers to healthcare access due to distance, limited financial resources, and weak health infrastructure. In Uganda, where over 5 million people live more than 5 km from a facility, these constraints lead to delayed care, underuse of essential services, and poorer health outcomes. Rural households often rely on informal providers, increasing the risk of inappropriate treatment. We implement a cluster-randomized controlled trial to evaluate the impact of improved healthcare access in rural Uganda. Working alongside a local organisation, we will test how two key factors influence the demand for healthcare: (1) distance—by randomising the timing of clinic openings in underserved areas to improve geographic access; and (2) cost—by offering free care to assess the role of financial barriers. We will use pictorial health diaries to collect high-frequency data on illness and care-seeking, and we will test for malaria positivity at endline. We will also examine how the arrival of new clinics affects the local healthcare market, including the number of drug shops and drug prices. By studying how proximity and affordability shape healthcare behaviour, this research will provide evidence to guide policies aimed at expanding access and reducing disease burden in low-resource settings.
External Link(s)

Registration Citation

Citation
Lagarde, Mylene. 2025. "Distance, price and healthcare use in rural areas." AEA RCT Registry. December 09. https://doi.org/10.1257/rct.17388-1.0
Experimental Details

Interventions

Intervention(s)
Working alongside a local NGO, we will test how two key factors influence the demand for healthcare:
(1) distance— here we test the impact of improving physical access to healthcare. Working with the NGO, we will randomise the timing of the opening of new clinics in remote, underserved villages, located 1-2 hours away from the nearest existing clinic. The clinics set up by the NGO provide nurse-led primary care, offering treatment for around 30 common conditions, and basic diagnostic tests such as malaria rapid tests. Nurses can also deliver urgent treatments—such as injectable medications or intravenous fluids—before referring severe cases to higher-level facilities. Clinics maintain a reliable stock of medicines and conduct monthly quality audits to ensure consistent, safe care. Patients pay a small flat fee (approximately $2 or UgX5,000), which covers consultation, diagnostic tests, and treatment.

(2) cost—this second intervention tests the role of financial barriers. In communities where a clinic is opened, we will cross-randomise access to care for free for some target children. Half of the participating households will be randomly assigned to receive a card granting free consultations for one child under five for the duration of the study. This allows the study to measure how reducing out-of-pocket costs affects demand for care.
Intervention Start Date
2025-07-01
Intervention End Date
2026-07-31

Primary Outcomes

Primary Outcomes (end points)
Probability of underuse of formal medical care by children under 5
Primary Outcomes (explanation)
Probability of underuse is calculated at the individual level as the ratio of the number of serious illness episodes for which care is recommended and sought over the total number of illness episodes for which care is recommended. To determine whether care is recommended in an illness episode, we will use the information about illness symptoms and apply WHO standards for community management of child illness.

Secondary Outcomes

Secondary Outcomes (end points)
Probability of overuse of healthcare for target child (seeking care during mild illness episode)
Medical expenditures (fees + drugs) for target child
Probability of using informal providers for target child
Health-related transport expenditures (eg spending on local transport to reach clinics) for target child
Formal and informal healthcare use for household members (conditional on being sick in past 4 weeks)
Proportion of household members testing positive for malaria at endline
Number of days of work (adult) or school (child) missed due to illness
Secondary Outcomes (explanation)

Experimental Design

Experimental Design
The study uses a paired-matched cluster randomisation design. Communities identified as eligible by the NGO to receive a clinic will be grouped into pairs based on similarity in need and feasibility. Within each pair, one community is randomly assigned to receive a new clinic, while the other serves as a control. This produces 20 control communities and 20 treated communities where a clinic will open.

In the 20 clinic communities, a second randomisation is conducted at the household level: among the 20 study households per village, half are randomly allocated to receive free care for one child, while the remaining half pay the usual clinic fees. This creates three experimental groups: pure control communities (no clinic), households in clinic communities with standard priced care, and households in clinic communities receiving free care.
Experimental Design Details
Not available
Randomization Method
Randomisation is done by a computer programme (Stata)
Randomization Unit
We will have 2 levels of randomisation: Villages for intervention 1 (clinic opening) and individuals for intervention 2 (free card)
Was the treatment clustered?
Yes

Experiment Characteristics

Sample size: planned number of clusters
40 villages
Sample size: planned number of observations
800 individuals (20 in each village)
Sample size (or number of clusters) by treatment arms
N=400 in the control arm, N=400 in treated villages (with clinics) ; within treated village, n=200 children will have access to free care, and the rest will not
Minimum detectable effect size for main outcomes (accounting for sample design and clustering)
● MDE of reduced distance: With 20 clusters per arm, assuming an intra-cluster correlation coefficient of 0.10 and that 80% of children have at least one serious illness episode over the duration of the study, we will have 16 individuals in control clusters and 8 in treated clusters, the trial is powered to detect a reduction of the probability of underuse by 18.6 percentage points from 50% in the control group (note that the proportion of 50% is chosen because it provides the most conservative detectable effect size; the MDE would be 16.9pp if the probability of underuse in control areas is 80%). ● MDE of reduced cost: In the treated clusters, we will follow a total of 400 households, half of whom will receive access to free care for their child for the duration of the study. Assuming that 80% of children have at least one serious illness episode over the duration of the study, the trial is powered to detect a reduction of 13.5 percentage points in the probability of underuse from 32% for households without free cards.
IRB

Institutional Review Boards (IRBs)

IRB Name
Research Ethics Committee LSE
IRB Approval Date
2025-04-07
IRB Approval Number
536041
IRB Name
Lacor Hospital Institutional REC
IRB Approval Date
2025-06-10
IRB Approval Number
LACOR-2025-2085