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Last Published April 19, 2026 09:06 AM April 21, 2026 03:00 PM
Planned Number of Observations Planned Number of Observations: 1,036 individual participants * 4 rounds = 4,144. N = 1,012 is chosen to achieve 80% power at alpha=0.05 for the primary Sure vs 10% contrast with MDE=0.20 under the prespecified unequal allocation. Planned Number of Observations: 1,140 individual participants * 4 rounds = 4,560. N = 1,012 is chosen to achieve 80% power at alpha=0.05 for the primary Sure vs 10% contrast with MDE=0.20 under the prespecified unequal allocation.
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