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Abstract
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Before
This study will explore whether financial incentives and reminders help improve anti-retroviral therapy (ART) adherence among HIV infected individuals. The interventions will be randomized in the study population in a cross-cutting design, with a control group, a financial incentive treatment group, a reminder phone call treatment group, and a treatment group that receives both reminder calls and financial incentives. This design allows estimation of complementarities between the two interventions. The primary outcome of interest will be adherence to ART, as measured by the medication possession ratio (MPR) over 6 months.
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After
The long-term goal is to understand the barriers that HIV patients in sub-Saharan Africa face in adhering to antiretroviral therapy (ART) and develop interventions to improve adherence that may be scaled up. Many people living with HIV in sub-Saharan Africa fail to adhere to ART, the medical treatment for HIV that can stop the virus from progressing to AIDS and also prevents transmission to others. This study seeks to identify the barriers to treatment adherence and develop interventions to improve adherence. We recruit patients who are newly diagnosed with HIV infection and prescribed ART from a large health center in Mozambique. For patients who meet the study qualifications, we randomly assign them to receive standard of care versus reminder phone calls, a monetary incentive or both. Other interventions aim to increase knowledge regarding HIV infection and decrease stigma. We track the medication possession ratio (MPR) after six months to evaluate the various interventions. To shed light on the spillovers of the interventions, we offer coupons for the participants to refer their partners to get tested. The experiment result will inform us of behavioral patterns of the population that are economically and physically vulnerable. Effective interventions are ready to be scaled up in HIV-treatment facilities in resource-constrained environments.
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Trial End Date
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Before
March 16, 2020
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After
August 16, 2021
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Last Published
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Before
August 23, 2019 01:51 PM
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After
March 03, 2020 07:46 AM
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Intervention End Date
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Before
March 11, 2019
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After
August 11, 2021
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Experimental Design (Public)
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Before
Participants will be randomized with equal probability to a control group, a financial incentive treatment group, a reminder phone call treatment group, and a treatment group that receives both reminder calls and financial incentives. The interventions will last for 6 months.
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After
Participants will be randomized with equal probability to a control group, a financial incentive treatment group, a reminder phone call treatment group, and a treatment group that receives both reminder calls and financial incentives, an anti-stigma intervention group, an HIV/ART knowledge intervention group, a group that receives both the anti-stigma and the knowledge intervention group. The financial incentive and the phone call reminder interventions will last for 6 months. The informational interventions are one-time conducted at the time of recruitment.
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Planned Number of Clusters
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Before
1200 individuals
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After
2100 individuals
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Planned Number of Observations
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Before
1200 individuals
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After
2100 individuals
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Sample size (or number of clusters) by treatment arms
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Before
300 individuals control, 300 individuals financial incentive, 300 individuals phone call reminders, 300 individuals both treatment.
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After
300 individuals control, 300 individuals financial incentive, 300 individuals phone call reminders, 300 individuals both the financial incentive and reminder intervention, 300 anti-stigma intervention, 300 HIV/ART knowledge intervention, 300 both anti-stigma and knowledge intervention
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