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Persuasion in Medicine: Experimental Evidence on Sender and Signal Effects

Last registered on October 16, 2019

Pre-Trial

Trial Information

General Information

Title
Persuasion in Health
RCT ID
AEARCTR-0004796
Initial registration date
October 15, 2019

Initial registration date is when the trial was registered.

It corresponds to when the registration was submitted to the Registry to be reviewed for publication.

First published
October 16, 2019, 10:26 AM EDT

First published corresponds to when the trial was first made public on the Registry after being reviewed.

Last updated
October 16, 2019, 7:36 PM EDT

Last updated is the most recent time when changes to the trial's registration were published.

Locations

Region

Primary Investigator

Affiliation
Harvard Kennedy School

Other Primary Investigator(s)

PI Affiliation
Stanford University

Additional Trial Information

Status
In development
Start date
2019-10-15
End date
2020-06-15
Secondary IDs
Abstract
Prior research has found that patient-doctor racial concordance is important for increasing the demand for preventive healthcare among low-income African American men, particularly for invasive services. Although results were consistent with better communication as the mechanism, other explanations, such as differential messaging or doctor quality, were difficult to exclude. To eliminate confounding from these factors and uncover which aspects of communication are particularly important for influencing health behaviors, we propose a pilot RCT randomizing black and white adult male subjects to infomercials featuring black and white male physician-actors. The content of the infomercial is the safety and effectiveness of adult seasonal flu vaccination. We hold the signal (i.e. the infomercial script) constant, while varying features of the sender (i.e. race and authority). By including black and white respondents, we test whether concordance effects differ across race. Our primary outcomes of interest are prior/posterior beliefs about the risk/benefits of the flu shot, perceptions of the sender, willingness-to-pay (WTP) for a free flu shot voucher, level of attention and recall from the infomercial video, and redemption of said voucher.
External Link(s)

Registration Citation

Citation
Alsan, Marcella and Sarah Eichmeyer. 2019. "Persuasion in Health." AEA RCT Registry. October 16. https://doi.org/10.1257/rct.4796-1.1
Sponsors & Partners

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Experimental Details

Interventions

Intervention(s)
The study subjects will be randomly assigned to one of several informational videos. Each video will contain one of black or white male actors playing the role of either a doctor or a layperson. The actors will be provided with a script of information to read. The script will be about the safety and effectiveness of adult seasonal flu vaccination. We will hold the signal (i.e. the infomercial script) constant, while varying features of the sender (i.e. race and authority). Through this intervention, we will test whether concordance effects differ across race and/or authority.
Intervention Start Date
2019-10-15
Intervention End Date
2020-02-29

Primary Outcomes

Primary Outcomes (end points)
Our primary outcomes of interest are prior/posterior beliefs about the risk/benefits of the flu shot, perceptions of the sender, willingness-to-pay (WTP) for a free flu shot voucher, level of attention and recall from the infomercial video, and redemption of said voucher.
Primary Outcomes (explanation)

Secondary Outcomes

Secondary Outcomes (end points)
Secondary Outcomes (explanation)

Experimental Design

Experimental Design
We will recruit approximately 1,400 African American or Caucasian male subjects aged 25-50 with a high-school diploma or less. We will oversample African American individuals, emphasizing low-income and minority men because these characteristics are correlated with lower relative take-up of flu vaccination. After informed consent is obtained, subjects will be asked about sociodemographic information (age, education, income and marital status), healthcare experience and past medical history, knowledge and beliefs about flu vaccination, and location of the nearest pharmacy. We will then randomly assign the adult male subjects to infomercials which contain one of black or white actors playing the role of either a doctor or a layperson. The content of the infomercial will be the safety and effectiveness of adult seasonal flu vaccination. After the video, we will ask subjects whether they would like to receive a free flu shot coupon. we will ask about their beliefs regarding flu vaccination and the video, and the willingness-to-pay for a flu shot coupon. We will track coupon redemption, which is redeemable at most pharmacies nationwide.
Experimental Design Details
Randomization Method
We are using computer randomization via Qualtrics.
Randomization Unit
The unit of randomization is the individual.
Was the treatment clustered?
No

Experiment Characteristics

Sample size: planned number of clusters
Not applicable
Sample size: planned number of observations
Approximately 1,400 men (980 African American men and 420 Caucasian men) will be recruited.
Sample size (or number of clusters) by treatment arms
Approximately 1,400 men will be recruited and randomly assigned with a 70% chance of being assigned to an infomercial featuring a physician-actor and a 30% chance of being assigned to an infomercial featuring a layperson-actor. Within each group, subjects will be randomly assigned to either a Caucasian or African American actor with a 50% chance.
Minimum detectable effect size for main outcomes (accounting for sample design and clustering)
This is a pilot study, where the sample size is determined by the budget and allows us to work on the feasibility and logistics of the intervention.
IRB

Institutional Review Boards (IRBs)

IRB Name
Harvard University
IRB Approval Date
2019-10-11
IRB Approval Number
IRB19-1424
Analysis Plan

Analysis Plan Documents

Post-Trial

Post Trial Information

Study Withdrawal

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Intervention

Is the intervention completed?
No
Data Collection Complete
Data Publication

Data Publication

Is public data available?
No

Program Files

Program Files
Reports, Papers & Other Materials

Relevant Paper(s)

Reports & Other Materials