Secondary Outcomes (explanation)
The first two secondary endpoints will be measured by adapting previously published and validated scales to assess trust in and perceived benefits of the hypothetical program described in the participant facing materials [1-3]. The comprehension endpoint will be measured using a series of multiple-choice questions (4 or 8 questions, depending on the treatment). For participants who do not receive the additional information covered in the trust or benefit conditions, the corresponding comprehension questions will be explicitly presented as opinion questions and are not counted in the comprehension score.
1. Platt, J., & Kardia, S. (2015). Public trust in health information sharing: implications for biobanking and electronic health record systems. Journal of Personalized Medicine, 5(1), 3-21.
2. Platt, J. E., Jacobson, P. D., & Kardia, S. L. (2018). Public trust in health information sharing: a measure of system trust. Health Services Research, 53(2), 824-845.
3. Ulrich, C. M., Zhou, Q., Ratcliffe, S. J., Knafl, K., Wallen, G. R., Richmond, T. S., & Grady, C. (2018). Development and preliminary testing of the perceived benefit and burden scales for cancer clinical trial participation. Journal of Empirical Research on Human Research Ethics, 13(3), 230-238.