Field
Power calculation: Minimum Detectable Effect Size for Main Outcomes
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Before
Primary outcome 1 (number of patients with co-prescriptions)
- MDE, arm-to-arm comparison: 0.19 patients (4.5% of mean)
- MDE, all interventional arms vs. control: 0.15 patients (3.7% of mean)
Primary outcome 2 (indicator for checking the PMP)
- MDE, arm-to-arm comparison: 2.2 percentage points (4.6% of mean)
- MDE, all interventional arms vs. control: 1.8 percentage points (3.7% of mean)
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After
Primary outcome 1 (number of patients with co-prescriptions)
- MDE, arm-to-arm comparison: 0.19 patients (5.1% of mean)
- MDE, all interventional arms vs. control: 0.15 patients (4.2% of mean)
Primary outcome 2 (indicator for checking the PMP)
- MDE, arm-to-arm comparison: 2.2 percentage points (4.5% of mean)
- MDE, all interventional arms vs. control: 1.8 percentage points (3.7% of mean)
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