COVID-19 Vaccine Acceptability in Mozambique

Last registered on February 18, 2021

Pre-Trial

Trial Information

General Information

Title
COVID-19 Vaccine Acceptability in Mozambique
RCT ID
AEARCTR-0007228
Initial registration date
February 18, 2021

Initial registration date is when the trial was registered.

It corresponds to when the registration was submitted to the Registry to be reviewed for publication.

First published
February 18, 2021, 6:50 AM EST

First published corresponds to when the trial was first made public on the Registry after being reviewed.

Locations

Region

Primary Investigator

Affiliation
Nova SBE and NOVAFRICA

Other Primary Investigator(s)

PI Affiliation
Nova SBE
PI Affiliation
Nova SBE

Additional Trial Information

Status
On going
Start date
2020-07-01
End date
2021-03-10
Secondary IDs
Abstract
In this paper, we study how to address two relevant threats to COVID-19 vaccines acceptability in Mozambique: the low level of trust in the national health system's capacity and the wild circulation of fake news. We survey by phone participants in two previous randomized controlled trials in the Great Maputo Area and Cabo Delgado's province. In the follow-up survey, we test three interventions over the phone, which we implement in a cumulating fashion. First, we convey a simple message endorsing vaccination against COVID-19. This message represents our benchmark intervention. Second, we add a statement praising a previous successful immunization campaign that eradicated wild polio to lever social memory. We test whether the memory of an earlier achievement can increase trust in the capacity to operationalize the vaccination campaign against COVID-19 successfully. Third, we add a simple pre-bunking intervention against fake news based on psychological inoculation. We first interactively raise awareness about how fake information about COVID-19 vaccines may generate and spread by asking the respondent to share her worst concerns. We then convey a message about the dangers of contributing to create and spread fake news. We hope to contribute with our findings to inform the Mozambican communication to increase COVID-19 vaccines as it approaches the country's first delivery date.
External Link(s)

Registration Citation

Citation
Armand, Alex , Mattia Fracchia and Pedro Vicente. 2021. "COVID-19 Vaccine Acceptability in Mozambique." AEA RCT Registry. February 18. https://doi.org/10.1257/rct.7228
Experimental Details

Interventions

Intervention(s)
Intervention Start Date
2021-02-18
Intervention End Date
2021-03-06

Primary Outcomes

Primary Outcomes (end points)
For endorsement message:
- Survey measures on trust in COVID-19 vaccines
- Survey measures on vaccine acceptability

Social memory message:
- Survey measures on trust in institutions
- Survey measures on stated willingness to get involved in the community
- Behavioural measure. Take advantage of the opportunity to send a message via SMS, which could include either praising or (negative) criticism,
to the Ministry of Health through the research team.

Pre-bunking intervention:
- Behavioural measure. Subscription to an SMS free service provided by the research team to receive regular updates on COVID-19 vaccination in
Mozambique
- Behavioural measure. Participation in an SMS service to help disseminate truthful information by sending SMS to the research team with
identified fake rumours about COVID-19. This service offers the possibility to provide a phone number to which the research team will forward the
correct information.
Primary Outcomes (explanation)

Secondary Outcomes

Secondary Outcomes (end points)
Secondary Outcomes (explanation)

Experimental Design

Experimental Design
We randomize three interventions over the phone during the follow-up survey. First, we convey a simple message endorsing vaccination against COVID-19. This message represents our benchmark intervention. Second, we add a statement praising a previous successful immunization campaign that eradicated wild polio to lever social memory. We test whether the memory of an earlier achievement can increase trust in the capacity to operationalize the vaccination campaign against COVID-19 successfully. Third, we add a simple pre-bunking intervention against fake news based on psychological inoculation. We first interactively raise awareness about how fake information about COVID-19 vaccines may generate and spread by asking the respondent to share her worst concerns. We then convey a message about the dangers of contributing to create and spread fake news. We cumulatively implement them, giving the resulting treatment arms:
• Control
• Endorsement message
• Endorsement message + social memory message
• Endorsement message + social memory message + Pre-bunking intervention
Experimental Design Details
Randomization Method
Randomization is done in Stata
Randomization Unit
Individual
Was the treatment clustered?
No

Experiment Characteristics

Sample size: planned number of clusters
862 individuals
Sample size: planned number of observations
862
Sample size (or number of clusters) by treatment arms
215
Minimum detectable effect size for main outcomes (accounting for sample design and clustering)
IRB

Institutional Review Boards (IRBs)

IRB Name
Nova School of Business and Economics
IRB Approval Date
2020-07-14
IRB Approval Number
N/A

Post-Trial

Post Trial Information

Study Withdrawal

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Intervention

Is the intervention completed?
No
Data Collection Complete
Data Publication

Data Publication

Is public data available?
No

Program Files

Program Files
Reports, Papers & Other Materials

Relevant Paper(s)

Reports & Other Materials