Impact of an educational campaign on pharmacists' beliefs and irresponsible dispensing of antimicrobials.

Last registered on August 13, 2021

Pre-Trial

Trial Information

General Information

Title
Impact of an educational campaign on pharmacists' beliefs and irresponsible dispensing of antimicrobials.
RCT ID
AEARCTR-0007570
Initial registration date
April 17, 2021
Last updated
August 13, 2021, 9:03 AM EDT

Locations

Region

Primary Investigator

Affiliation

Other Primary Investigator(s)

Additional Trial Information

Status
On going
Start date
2019-08-26
End date
2021-11-30
Secondary IDs
Prior work
This trial does not extend or rely on any prior RCTs.
Abstract
This trial evaluates an educational intervention carried out on medical store workers in Bihar, India. Over 670 medical store workers were surveyed to evaluate their knowledge on correct drug dispensing protocols and their beliefs on antimicrobial resistance as a public health threat. Randomly selected workers received an informational intervention consisting of the recommended WHO`s dispensing protocol, statistics on antibiotic resistance prevalence and its consequences in India and a reminder of the legal status of unnecessary antibiotics dispensing.
External Link(s)

Registration Citation

Citation
Zarate, Pablo. 2021. "Impact of an educational campaign on pharmacists' beliefs and irresponsible dispensing of antimicrobials.." AEA RCT Registry. August 13. https://doi.org/10.1257/rct.7570-1.2000000000000002
Experimental Details

Interventions

Intervention(s)
Intervention Start Date
2019-09-09
Intervention End Date
2019-09-25

Primary Outcomes

Primary Outcomes (end points)
Define AMR, Define Antibiotics, Dispensing Index, Pharmacist Responsibility, Deny ABs, Relation AB and ABR, Feel Knowledgeable, Take Time, Importance AMR, Check Prescription, Partial Dose, Demand Antibiotics Valid Prescription
Primary Outcomes (explanation)

Secondary Outcomes

Secondary Outcomes (end points)
Secondary Outcomes (explanation)

Experimental Design

Experimental Design
Medical stores in those cities participated in up to three stages: a baseline, an intervention and an endline. India has the particular characteristic of having multiple recognized traditional systems of medicines, like Ayurveda, Siddha, or Homoeopathy (Ravishankar and Shukla, 2007), which do not rely on allopathic medications, such as Antibiotics. However, rather than excluding stores based on their marketing or names, the inclusion criteria for a medical store (worker) to participate in our study included a) the presence of antibiotics for sale in the store at the moment the baseline survey was conducted and b) acknowledgement by the workers at the pharmacy that the
survey respondent was (one of) the de facto dispenser(s) of antibiotics in the store, regardless of quali cations.
Out of the 670 workers ocially surveyed in the baseline, we randomly divided our sample into two sub-groups: those who were to receive our intervention (treatment group) and those who would not (control group). Given our effective 1-to-1 mapping of medical store and pharmacist, our randomization at an individual level is equivalent to a randomization at a shop level.
Experimental Design Details
Not available
Randomization Method
Randomization done in office by a computer
Randomization Unit
Medical Store
Was the treatment clustered?
No

Experiment Characteristics

Sample size: planned number of clusters
700 medical stores
Sample size: planned number of observations
700 medical stores
Sample size (or number of clusters) by treatment arms
350 medical stores receive the educational Intervention, 350 medical stores are control
Minimum detectable effect size for main outcomes (accounting for sample design and clustering)
IRB

Institutional Review Boards (IRBs)

IRB Name
Ethikkommission University Göttingen
IRB Approval Date
2019-03-25
IRB Approval Number
N/A