The effect of Multi domain cognitive training on Cognitive impairment and Dementia in Blinds

Last registered on December 21, 2023

Pre-Trial

Trial Information

General Information

Title
The effect of Multi domain cognitive training on Cognitive impairment and Dementia in Blinds
RCT ID
AEARCTR-0012712
Initial registration date
December 17, 2023

Initial registration date is when the trial was registered.

It corresponds to when the registration was submitted to the Registry to be reviewed for publication.

First published
December 21, 2023, 7:56 AM EST

First published corresponds to when the trial was first made public on the Registry after being reviewed.

Locations

Region

Primary Investigator

Affiliation
FUSST

Other Primary Investigator(s)

PI Affiliation
FUSST
PI Affiliation
FUSST
PI Affiliation
FUSST

Additional Trial Information

Status
On going
Start date
2023-12-01
End date
2024-01-05
Secondary IDs
Prior work
This trial does not extend or rely on any prior RCTs.
Abstract
The main goal of this study is to determine whether implementing this intervention results in any appreciable improvements in the levels of dementia, depression, and cognitive impairment that have been measured. With the aid of this research methodology, the present study examines the relationship that may exist between cognitive functioning, and the onset of dementia in blind people, providing insight into the success of the intervention in enhancing their overall cognitive function. Form a cognitive test for the blind individual.
External Link(s)

Registration Citation

Citation
Habib, Yusra et al. 2023. "The effect of Multi domain cognitive training on Cognitive impairment and Dementia in Blinds." AEA RCT Registry. December 21. https://doi.org/10.1257/rct.12712-1.0
Experimental Details

Interventions

Intervention(s)
As mentioned, the intervention covered a broad range of cognitive domains with tasks that involved reasoning, memory, visuospatial skills, and attention. The cognitive training program was developed by the Foundation University School of Science and Technology. The intervention was carried out at the Government Institute. The whole intervention comprised of a training session delivered once. The session included tasks that focused on cognitive domains. The cognitive training program covered the domains of memory (e.g., memorizing pictures and words, adapted from the word learning test and digit span test). Each task contained 3–5 different levels of difficulty, with 4 trials in each difficulty level. If a participant answered correctly in four or more trials, the difficulty level would be increased; conversely, if a participant answered incorrectly in more than two trials, the difficulty level in the next trial would be decreased.
Intervention Start Date
2023-12-01
Intervention End Date
2023-12-31

Primary Outcomes

Primary Outcomes (end points)
The study assessed cognition both at the baseline and after the intervention. Based on a survey of neuropsychological assessment, this study designed a cognitive test that examined memory, reasoning, visuospatial ability, attention, processing speed, and executive functioning. The individual tests are listed below. Global cognition was assessed via the MMSE (Folstein et al., 1975) and Cognitive test. The Cognitive test is further divided into 5 task such as Block design, Object assembly, pattern recognition, Labyrinth, Card arrangement.
Primary Outcomes (explanation)
The study assessed cognition both at the baseline and after the intervention. Based on a survey of neuropsychological assessment, this study designed a cognitive test that examined memory, reasoning, visuospatial ability, attention, processing speed, and executive functioning. The individual tests are listed below. Global cognition was assessed via the MMSE (Folstein et al., 1975) and Cognitive test. The Cognitive test is further divided into 5 task such as Block design, Object assembly, pattern recognition, Labyrinth, Card arrangement.

Secondary Outcomes

Secondary Outcomes (end points)
Dementia , Depression
Secondary Outcomes (explanation)
Dementia Severity Rating Scale
The Dementia Severity Rating Scale is a 5-point scale used to characterize six domains of cognitive and functional performance applicable to Alzheimer disease and related dementias: Memory, Orientation, Judgment & Problem Solving, Community Affairs, Home & Hobbies, and Personal Care. The necessary information to make each rating is obtained through a semi structured interview of the patient and a reliable informant or collateral source.

Beck Depression Inventory:
The Beck Depression Inventory (BDI, BDI-II), created by Dr. Aaron T. Beck, it’s a 21-question multiple-choice self-report inventory, one of the most widely used instruments for measuring the severity of depression. Its development marked a shift among health care professionals, who had until then viewed depression from a psychodynamic perspective, instead of it being rooted in the patient’s own thoughts.

Experimental Design

Experimental Design
The 72 item BCIT was administered by performing each task in a lab . Each participant was first asked to fill in a consent form and answer demographic questions before preceding to answering the BCIT. The BCIT was the first of a series of task to be perform by the participants. The remaining half item of task were always presented after the Multi domain cognitive training.
Experimental Design Details
Randomization Method
Randomization done at Government institute.
Randomization Unit
Unit of randomization is Blind school.
Was the treatment clustered?
Yes

Experiment Characteristics

Sample size: planned number of clusters
5 to 6 blind school.
Sample size: planned number of observations
60 pupils
Sample size (or number of clusters) by treatment arms
30 blind student and 30 normal students
Minimum detectable effect size for main outcomes (accounting for sample design and clustering)
Supporting Documents and Materials

Documents

Document Name
Blind cognitive Intelligent test
Document Type
proposal
Document Description
File
Blind cognitive Intelligent test

MD5: 0b14f95852e33be3964e7833f8fb14e4

SHA1: b73f3fdcc575b953b8794ec3ae859139428c0d83

Uploaded At: December 17, 2023

IRB

Institutional Review Boards (IRBs)

IRB Name
IRB Approval Date
IRB Approval Number

Post-Trial

Post Trial Information

Study Withdrawal

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Intervention

Is the intervention completed?
No
Data Collection Complete
Data Publication

Data Publication

Is public data available?
No

Program Files

Program Files
Reports, Papers & Other Materials

Relevant Paper(s)

Reports & Other Materials