Interventions to Improve HIV Antiretroviral Therapy Adherence in Beira, Mozambique
Last registered on September 11, 2018

Pre-Trial

Trial Information
General Information
Title
Interventions to Improve HIV Antiretroviral Therapy Adherence in Beira, Mozambique
RCT ID
AEARCTR-0003184
Initial registration date
September 10, 2018
Last updated
September 11, 2018 8:43 AM EDT
Location(s)

This section is unavailable to the public. Use the button below to request access to this information.

Request Information
Primary Investigator
Affiliation
University of Michigan
Other Primary Investigator(s)
PI Affiliation
University of Michigan
PI Affiliation
University of Michigan
Additional Trial Information
Status
On going
Start date
2018-08-06
End date
2020-03-16
Secondary IDs
clinicaltrials.gov: NCT03618511
Abstract
This study will explore whether financial incentives and reminders help improve anti-retroviral therapy (ART) adherence among HIV infected individuals. The interventions will be randomized in the study population in a cross-cutting design, with a control group, a financial incentive treatment group, a reminder phone call treatment group, and a treatment group that receives both reminder calls and financial incentives. This design allows estimation of complementarities between the two interventions. The primary outcome of interest will be adherence to ART, as measured by the medication possession ratio (MPR) over 6 months.
External Link(s)
Registration Citation
Citation
Riddell, James, Dean Yang and Hang Yu. 2018. "Interventions to Improve HIV Antiretroviral Therapy Adherence in Beira, Mozambique." AEA RCT Registry. September 11. https://www.socialscienceregistry.org/trials/3184/history/34049
Experimental Details
Interventions
Intervention(s)
Intervention Start Date
2018-08-06
Intervention End Date
2019-03-11
Primary Outcomes
Primary Outcomes (end points)
Medication possession ratio (MPR) at least 95%, 6-month window
Primary Outcomes (explanation)
Secondary Outcomes
Secondary Outcomes (end points)
Secondary Outcomes (explanation)
Experimental Design
Experimental Design
Participants will be randomized with equal probability to a control group, a financial incentive treatment group, a reminder phone call treatment group, and a treatment group that receives both reminder calls and financial incentives. The interventions will last for 6 months.
Experimental Design Details
Not available
Randomization Method
Randomization done in the office by a computer.
Randomization Unit
Individual
Was the treatment clustered?
No
Experiment Characteristics
Sample size: planned number of clusters
1200 individuals
Sample size: planned number of observations
1200 individuals
Sample size (or number of clusters) by treatment arms
300 individuals control, 300 individuals financial incentive, 300 individuals phone call reminders, 300 individuals both treatment.
Minimum detectable effect size for main outcomes (accounting for sample design and clustering)
IRB
INSTITUTIONAL REVIEW BOARDS (IRBs)
IRB Name
University of Michigan Medical School Institutional Review Board (IRBMED)
IRB Approval Date
2017-11-30
IRB Approval Number
HUM00133179