Risk beliefs, intensive information and demand for preventative health care

Last registered on August 29, 2024

Pre-Trial

Trial Information

General Information

Title
Risk beliefs, intensive information and demand for preventative health care
RCT ID
AEARCTR-0014204
Initial registration date
August 19, 2024

Initial registration date is when the trial was registered.

It corresponds to when the registration was submitted to the Registry to be reviewed for publication.

First published
August 29, 2024, 11:33 AM EDT

First published corresponds to when the trial was first made public on the Registry after being reviewed.

Locations

Region

Primary Investigator

Affiliation

Other Primary Investigator(s)

PI Affiliation
Imperial College London

Additional Trial Information

Status
Completed
Start date
2019-07-01
End date
2020-07-30
Secondary IDs
Prior work
This trial does not extend or rely on any prior RCTs.
Abstract
This randomised-controlled experiment tested the hypothesis that demand for a recently available, free HIV prevention product responds to a combination of – adjustment of prior beliefs on relatives risks of HIV infection and benefits of prevention and clinic referral enabling access to the product. The preventative health product of interest is Pre-exposure Prophylaxis for HIV (PrEP). The experiment took place in 6 communities in Manicaland Province, Eastern Zimbabwe. The communities include two peri-urban small towns, three rural communities and one high-density urban suburb. Each community is served by one or more health care facilities that offers HIV services. Baseline data were gathered between July 2018 and December 2019.

The intervention comprised three parts – an intensive information component, sign-up for a call with a nurse to discuss PrEP and provision of a clinic referral for PrEP initiation. The information component involved a digital self-administered feedback-based quiz on relative risks of HIV infection and reduction in risks from condom use and PrEP. Following this, individuals could sign-up for a call with nurse from their local clinic to discuss PrEP. Finally, individuals were provided with a referral to their local clinic to initiate PrEP. The primary outcome was take-up of PrEP within six months. Secondary outcomes include the effects on risk beliefs and sexual behaviour. A rare feature of the study is the availability of baseline measures of time preferences, measured with monetarily incentivized economic experiments. This allows analysis of heterogeneity in demand for prevention by present-biased preferences.

Registration Citation

Citation
Gregson, Simon and Ranjeeta Thomas. 2024. "Risk beliefs, intensive information and demand for preventative health care." AEA RCT Registry. August 29. https://doi.org/10.1257/rct.14204-1.0
Experimental Details

Interventions

Intervention(s)
Intervention Start Date
2019-07-01
Intervention End Date
2020-07-30

Primary Outcomes

Primary Outcomes (end points)
Proportion of women taking up PrEP within six months, gathered from clinic data and triangulated with self-reports and biomarkers of PrEP presence from DBS.
Primary Outcomes (explanation)

Secondary Outcomes

Secondary Outcomes (end points)
Secondary Outcomes (explanation)

Experimental Design

Experimental Design
Two arm cluster randomised trial.
Experimental Design Details
Randomization Method
Coin flip.
Randomization Unit
Clusters of villages with each community.
Was the treatment clustered?
Yes

Experiment Characteristics

Sample size: planned number of clusters
12 clusters of villages
Sample size: planned number of observations
~ 650 women ie ~ 55 individuals per cluster.
Sample size (or number of clusters) by treatment arms
6 per arm
Minimum detectable effect size for main outcomes (accounting for sample design and clustering)
IRB

Institutional Review Boards (IRBs)

IRB Name
Medical Research Council of Zimbabwe (reference number: MRCZ/A/2243)
IRB Approval Date
Details not available
IRB Approval Number
Details not available

Post-Trial

Post Trial Information

Study Withdrawal

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Intervention

Is the intervention completed?
No
Data Collection Complete
Data Publication

Data Publication

Is public data available?
No

Program Files

Program Files
Reports, Papers & Other Materials

Relevant Paper(s)

Reports & Other Materials